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PLAB 1 / UKMLA AKT sample questions with answers
The PLAB 1 / UKMLA Applied Knowledge Test is a crucial step for international medical graduates seeking GMC registration to practise in the UK. To help you prepare effectively, we've compiled a selection of sample questions across various difficulty levels. Each question is followed by an answer and a detailed explanation to enhance your understanding.
Easy-level sample questions
Question 1
A 45-year-old male presents with chest pain and shortness of breath. Which of the following is the most appropriate initial investigation?
- A) Chest X-ray
- B) Electrocardiogram (ECG)
- C) Echocardiogram
- D) Cardiac enzymes
Answer: B) Electrocardiogram (ECG) Explanation: The initial investigation for a patient presenting with chest pain and shortness of breath should be an ECG to assess for any cardiac abnormalities, such as ischaemia or arrhythmias.
Question 2
What is the first-line treatment for hypertension in a patient with type 2 diabetes?
- A) Beta-blockers
- B) ACE inhibitors
- C) Calcium channel blockers
- D) Diuretics
Answer: B) ACE inhibitors Explanation: ACE inhibitors are the first-line treatment for hypertension in patients with type 2 diabetes due to their renal protective effects.
Moderate-level sample questions
Question 3
A 30-year-old woman presents with a 3-month history of fatigue and palpitations. Blood tests reveal a low haemoglobin level and a high mean corpuscular volume (MCV). What is the most likely diagnosis?
- A) Iron deficiency anaemia
- B) Vitamin B12 deficiency anaemia
- C) Thalassaemia
- D) Aplastic anaemia
Answer: B) Vitamin B12 deficiency anaemia Explanation: The combination of fatigue, palpitations, low haemoglobin, and high MCV suggests macrocytic anaemia, most commonly due to vitamin B12 deficiency.
Question 4
Which of the following is a common side effect of long-term corticosteroid use?
- A) Hyperkalemia
- B) Osteoporosis
- C) Hypertension
- D) Hypoglycaemia
Answer: B) Osteoporosis Explanation: Long-term use of corticosteroids is associated with an increased risk of osteoporosis due to their effect on calcium metabolism and bone density.
Advanced/hard sample questions
Question 5
A 60-year-old male with a history of smoking presents with a persistent cough and weight loss. A chest CT scan reveals a mass in the right lung. Which of the following is the most appropriate next step in management?
- A) Observation
- B) Bronchoscopy
- C) Chemotherapy
- D) Surgical resection
Answer: B) Bronchoscopy Explanation: In cases of suspected lung cancer, bronchoscopy is often the next step to obtain tissue for diagnosis before considering treatment options.
Question 6
A patient with severe asthma is being treated with high-dose inhaled corticosteroids. What is the most significant risk associated with this treatment?
- A) Hyperglycaemia
- B) Adrenal insufficiency
- C) Osteoporosis
- D) Infection
Answer: B) Adrenal insufficiency Explanation: High-dose inhaled corticosteroids can lead to adrenal suppression, particularly if used long-term, necessitating monitoring for adrenal insufficiency.
How to interpret distractors
In multiple-choice questions, distractors are incorrect options designed to challenge your knowledge. When tackling these questions, consider the following strategies:
- Elimination: Remove clearly wrong answers first.
- Contextual clues: Use the information given in the question to guide your choice.
- Knowledge recall: Rely on your medical knowledge to assess the plausibility of each option.
Understanding how to identify and interpret distractors can significantly improve your performance in the PLAB 1 / UKMLA AKT.
Take a free full mock test
To further enhance your preparation, consider taking a free full mock test available on PractiseExam.com. This will provide you with a realistic exam experience and help you identify areas where you may need additional study. Mock tests are an excellent way to assess your readiness and familiarise yourself with the exam format.
For additional resources, including the syllabus and preparation strategies, visit our related links. Ensure you’re well-prepared for the PLAB 1 / UKMLA AKT by utilising all available study tools.